If you are confused about the acronyms that you encounter in medicine, you are not alone! Unfortunately, the acronyms surrounding menopause are no different. To add to the confusion, it doesn’t help that you may read a blog post or article about MHT, and then read a different article that sounds like it’s talking about the same thing but the author uses the term HRT. Confusing, right? Spoiler alert: they are all (kind of) the same thing.
MHT, HRT, and HT refer to hormones used to treat estrogen, progesterone and sometimes testosterone deficiency. The underlying cause of the low hormone levels or "deficiency" determines which acronym is used in medical jargon.
MHT is used to indicate hormone replacement associated with natural menopause. The average age of menopause in US women is age 52, but natural menopause can occur anytime between age 45 and 55 years old. Â
HRT is used to reference hormones prescribed due to early or premature menopause. Early is menopause occurring between age 40-45 years old, and premature is menopause before age 40 years old. Early and premature menopause may be the result of a medical condition such as “premature ovarian insufficiency” or it could be due to treatments like chemotherapy or radiation that may damage the ovaries and interfere with their ability to produce hormones. Surgical removal of the ovaries before age 45 is yet another reason to prescribe HRT. Â
HT is used interchangeably with MHT and often HRT as well.  Â
At Midlife Medicine, you will largely hear us using the term “hormone therapy” but know that MHT, HRT and HT are not significantly different from each other in practice. The reason for the prescribed hormone(s) is the main difference in the terminology.